DNA Cot-I, human at Wholesale Price

Product name:DNA Cot-I, human
Description of DNA Cot-I, human:
Synonym:Cot-1 DNA, human
Human DNA Cot-I is prepared exclusively from human placental DNA (male fetus only) by shearing, denaturing, and reannealing under conditions that enrich repetitive elements. Therefore Cot-I fraction of human genomic DNA predominatly consists of rapidly annealing repetitive elements. COT I Human DNA can be used for suppressing crosshybridization to human repetitive DNA in filter and microarray hybridizations and in in situ hybridization experiments. Repetitive elements present in a probe may result in unspecific hybridization signals. To enable specific hybridization of the probe to the chromosomal target site the probe is denatured together with an excess of unlabeled Cot-I human DNA as a competitor. As a result single-copy gene hybridization is not hindered by repetitive sequences. The sample as well as the original material were tested for the absence of HIV1- and 2-RNA, HCV-RNA, HBV-DNA.
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