Useful Information of Nonactin

Product name:Nonactin
CAS:6833-84-7
Molecular formula:C40H64O12 (Nonactin)
Molecular weight:736.93 g/mol
Description of Nonactin:
Nonactin is part of a cyclic ionophore and Liuyangmycin class family of antibiotics.This ionophore is usually generated by several species of Streptomyces, the selective binding of K and NH4. Nonactin has a combination of a metal carrier and transport to the release of membrane function. Due to the conformational flexibility and external hydrophobic compounds functional implementation of transport. The compound formed a natural diastereomer can be used to its antibacterial and constrained sexuality.
Concentration of 1x10-7 M, Nonactin decoupling of oxidative phosphorylation induced by ATP hydrolysis. The compounds specifically inhibit the cytoplasmic precursor proteins destined for mitochondria. The presence of acetic acid the original explants, when compared to the acetate of the original explant alone, Nonactin can further stimulate the expansion of the rat liver mitochondria. , It can inhibit the effect of chemotherapy P170 glycoprotein-mediated drug efflux in MDR tumor cells. Nonactin can inhibit IL-5 rather than IL-2 and IL-4 production and gene transcription. Biosensor to establish the potential electrode and fluorescence immunoassay Nonactin as a detection of ammonium ion, ammonium ion carrier, in order to detect the K ions in pharmaceutical samples.
More about:Buy Nonactin